Bob Miller’s Interview with Dr. Mercola

Functional genetics looks at the single nucleotide polymorphisms (SNPs, pronounced “snips”) of genes. When you have SNPs (genetic variants or defects on the genes), enzymes may not be working effectively, or the gene may be upregulated or downregulated. While traditional genetics often looks for potential disease states, functional genetics looks for potential impairment of function and helps find the best nutritional intervention to bring your body back into balance. People with genetic weaknesses that hamper detoxification who are exposed to high amounts of environmental toxins can be struggling with health due to their limited ability to detoxify. NutriGenetic Research Institute is devoted to functional genomic testing, training health professionals to help people understand the results and how to apply it to improve their health Interviews Bob Miller

Episode #86: Lyme Genomics Update with Dr. Bob Miller, CTN

December 11, 2018, AKA Scott, is a Diplomat of Pastoral Science with the Pastoral Medical Association and feels that through his journey, he has been called to help others struggling to regain their health. Since his own diagnosis of Lyme disease in mid-2005, he has attended a number of medical conferences, has written a number of articles for the Public Health Alert, has spoken at various events, and has had the opportunity to interview some of the world’s top doctors and learn about their approaches to treating chronic illness.

Key Takeaways

  • What is the role of iron over-absorption in chronic illness?

  • What role do glutamate and GABA play? What about glutamine?

  • What are mTOR and autophagy?

  • How big of an issue is mast cell activation syndrome?

Lyme Ninja Radio Interviews Bob Miller

Episode #166: Bob Miller, ND - Latest Findings in Genetic Nutrition

January 4, 2018

In this episode you will learn:

• The most important part of the immune system you've never heard of.
• Why its crucial to incorporate a “cleaning period” into your healing process
• Why balancing your mTOR is critical Interviews Bob Miller

Episode #44: Lyme Genomics with Bob Miller, CTN

September 18, 2017

Listen below to this eye-opening interview with Bob Miller, CTN on common genetic variants that are prevalent in those with chronic in Lyme disease. Some of this information will challenge our previously understood ideas.

Key Takeaways

  • What genetic patterns are more common in those with Lyme disease as compared to the 1000 Genomes Project?

  • Are today's health challenges more of a genetic issue or an epigenetic issue?

  • Why is supporting methylation not always a good idea?

  • Which genes impact iron absorption at higher levels in Lyme patients and lead to hydroxyl radical production?

NutriGenetic’s Founder Speaks at International Seminar on Chronic Lyme Disease & Genetics

April 24, 2017

Expanding his international audience, Bob Miller, CTN presented the NutriGenetic Research Institute’s latest ground-breaking research related to chronic Lyme disease and why the some patients remain ill to the Nordic Network for Vector-borne Diseases (NorVect) in Oslo, Norway. NorVect, a Nordic non-profit organization, is dedicated to building and sharing vital knowledge about vector-borne diseases, particularly in the fields of diagnostics and treatment. The seminar, offered free of charge, was held for professionals working in the health sector, patients and others with interest in the field.

Presentation Overview – One of the confusing situations with Lyme disease is that some people respond quickly to treatment, while others cannot tolerate the treatment or continue to have less than optimal outcomes. In this seminar, Bob Miller explored why genetic conditions may be a contributing factor to poor detoxification pathways and lowered immunity. He presented information discovered by the NutriGenetic Research Institute’s two Chronic Lyme and Genetics studies on the genetic patterns of those with Chronic Lyme, and how nutritional interventions can offer compensating mechanisms and may be supportive of conventional treatment.

Watch his full presentation, “Lyme disease – are your genes making you ill?” here.

Lyme Ninja Radio Interviews Bob Miller

Episode #143: Bob Miller, ND - Phase III Lyme Study: New Insights Into Genetic Nutrition

March 8, 2017

In this episode you will learn:

  • NEW information Bob has uncovered in his Phase III Lyme Study

  • Two major genetic variants that he sees in people with Lyme Disease

  • The toxic state Lyme Disease puts us in that prevents treatments from being effective

Lyme Disease UK Interviews Bob Miller

April 10, 2017 

Founder of NutriGenetic Research Institute Bob Miller, CTN, was interviewed live by Lyme Disease UK, a not-for-profit patient support network for Lyme disease sufferers and their loved ones around the United Kingdom. In this video, he answers many questions from Lyme Disease UK members and explains his work in nutrigenomics and complementary medicine.

Watch his interview with Lyme Disease UK here.

Lyme Ninja Radio Interviews Bob Miller

Episode #98: Bob Miller, N.D. - Nutrigenetic patterns of people with chronic Lyme Disease

November 12, 2016

In this episode you will learn:

  • Why you can have high iron and still be anemic

  • Why just supplementing methylated folate, even if you have the homozygous MTHFR gene, is probably a bad idea.

  • The excess nutrient that many Lymies have that makes them stay up way too late researching lyme

NutriGenetic Research Institute Wins International Award in Helsinki

Honored by European ILADS 2016 Conference for Outstanding Lyme Research Presentation

June 22, 2016

NutriGenetic Research Institute received one of two prestigious Lyme Poster Awards at the 2016 European ILADS (International Lyme and Associated Disease Society, Conference in Helsinki, Finland on June 11 for its outstanding  Lyme research presentation, “Higher Levels of Genetic Variants (SNPs) Found in those with Chronic Lyme Disease.” ILADS promotes understanding of Lyme and its associated diseases through education, awareness and action, and strongly supports physicians and other health care professionals dedicated to advancing the standard of care for Lyme and its associated diseases. Participation at the conference was by invitation only, and NutriGenetic Research Institute secured its place as one of the conference’s poster presenters by submitting a detailed research abstract. Poster presentations are common in scientific and research fields to present key findings to a large group of scholars, talk to and receive feedback from interested viewers. The Institute’s founder and primary researcher, Bob Miller, presented the research methodology and findings at the conference, and was on hand to receive the award. “I am very proud and honored to have had the opportunity to present at ILADS and receive this award,” exclaimed Bob Miller. “There is a real and dire need for answers within the Lyme community, particularly why some patients with chronic Lyme disease fail to get better with their physician-directed treatment protocol.”


As a traditional naturopath, Bob sees clients every day who are struggling, offering nutritional support to complement their standard medical care. For the past several years, he has been engaged with genetic variants and related research and is astounded at how many peoples’ health concerns are related to genetic issues. In 2015, Bob founded the NutriGenetic Research Institute to research and publish reports on the relationship between genetic variants and labs and presenting symptoms.

“Many of my clients have Lyme disease,” Bob explained. “Everyone has some level of genetic variation in their DNA and is susceptible, in their own unique way, especially if they have excessive amounts of variants. These variants can impact your ability to make and use different nutrients critical for: detoxification, mitochondrial function, limiting free radical production, ammonia removal, DNA repair, and much more. The net result can be increased inflammation, decreased energy, brain fog, and other adverse symptoms that compromise vitality and quality of life. With the genetic variant patterns I was seeing in clients, I wanted to test my theory and investigate the possible correlation of genetic variants with those dealing with chronic Lyme disease and the production of an oxidizing and immune weakening molecule called peroxynitrite, iron oxidation that creates hydroxyl radicals, lowered ammonia clearing, and weakened DNA repair genes. My goal was to identify how genetic variants may be holding back chronic Lyme disease patients from responding effectively to their physicians’ prescribed medical treatment.”

Every year in the U.S. alone, more than 300,000 people contract Lyme disease per the CDC. Those who are untreated, undertreated or misdiagnosed and treated late can develop severe lingering symptoms. The CDC estimates a range of 10-20% are diagnosed, treated and remain ill, while another study reports 36% who were diagnosed and treated upon having the EM bulls-eye rash and remained ill (Aucott 2013). ILADS published new treatment guidelines that contained a rigorous assessment of the evidence and found treatment failure rates ranging from 16% to 39% for early treatment. Estimates for patients with chronic Lyme disease are much higher, ranging from 26% to 50% (Johnson 2004). The ILADS website quick facts page indicates that 40% of Lyme patients end up with long-term health problems, and short treatment courses have resulted in upwards of a 40% relapse rate, especially if treatment is delayed. Based on these varying statistics, there may be upwards of 30,000 to 150,000 new people each year suffering from chronic Lyme disease in the U.S., with potentially an equal amount of those in Europe and more around the world. For everyone affected, the NutriGenetic Research Institute’s findings offer hope.

To conduct the study, NutriGenetic Research Institute asked for volunteers with chronic Lyme disease to submit their 23andMe genome (raw data) and complete a survey regarding what tick-borne diseases they have, how long they have been treating and rate a short list of symptoms to indicate severity. NutriGenetic Research Institute compared the entire group of nearly 200 participants with chronic Lyme disease to a control group of equal size; no one was studied individually and all participants’ data was kept confidential.

NutriGenetic Research Institute’s findings mirrored Bob Miller’s initial theory, indicating that those with chronic Lyme share similar genetic variants that impact mitochondrial function and iron oxidation related to Hemochromatosis Genes (potential over absorption of iron), weaken the urea cycle that impedes the clearing of ammonia, hinder genes that support DNA repair when damage occurs, deter the detoxing of pesticides, and finally, allow higher levels of glutamate to circulate in the body that can cause anxiety and inflammation.  The study shows potential for having a positive and substantive impact on the future care and treatment of patients with chronic Lyme disease if nutritional therapy is added to compensate for the variants, thus creating more favorable conditions for the medical treatment administered by licensed physicians to be effective. These findings are not a cure for Lyme disease, but hold promise to be a complementary therapy to assist the medical care to be more effective. After seeing these findings, NutriGenetic Research Institute wants to repeat the study with a larger base of those dealing with chronic Lyme, broaden the list of genes studies, and if possible, find a way to gather lab data that would verify the genetic findings. The goal is to have this report completed before the ILADS November 2016 conference being held in Philadelphia, PA.

NutriGenetic Research Institute founder, Bob Miller, is a Certified Traditional Naturopath with 20+ years of practice. He is also the founder and a practitioner at Tree of Life (, a practice in Ephrata, PA that offers the area’s widest array of naturopathic and holistic health services including: genetic nutritional consultations; naturopathic consultations; nutrition and dietary consults; fertility optimization and prenatal wellness; exercise and weight loss; structural therapy; reflexology; detoxification therapies; life coaching; and water and air purification.

Read the final findings of the Chronic Lyme & DNA Study.  

NutriGenetic Research Institute Invited to Present at ILADS European 2016 Conference

May 12, 2016

NutriGenetic Research Institute’s Abstract, “Higher Levels of Genetic Variants (SNPs) Found in those with Chronic Lyme Disease,” has been chosen for a poster presentation in the upcoming ILADS Helsinki, Finland 2016 conference.

View the poster presentation.